| 21-02, 18:15 |  Granada CF – Valencia CF |
22% | 30% | 48% | X2 | 2.86 | 3.17 | 2.47 | |||
| 21-02, 18:15 | Athletic Bilbao – Real Sociedad |
45% | 26% | 29% | 1 | 1.71 | 3.60 | 4.79 | |||
| 21-02, 18:45 | Wadi Degla SC – Enppi Club |
25% | 51% | 23% | 1X | 2.66 | 2.76 | 2.56 | |||
| 21-02, 19:15 | FC Porto – Moreirense FC |
62% | 14% | 25% | 1 | 1.16 | 6.25 | 16.76 | |||
| 21-02, 20:00 | KACM Marrakesh – RCA Raja Casablanca Athletico |
24% | 48% | 28% | X2 | 2.96 | 2.48 | 2.45 | |||
| 21-02, 20:30 | Atletico Madrid – Villarreal CF |
59% | 27% | 14% | 1 | 1.45 | 3.95 | 7.79 |
