| 17-12, 20:00 |  SC Paderborn 07 – FC Schalke 04 |
23% | 22% | 55% | 2 | 10 | 2.72 | 3.35 | 2.47 | ||
| 17-12, 20:00 | RCD Espanyol Barcelona – CD Alaves |
70% | 17% | 13% | 1 | 1.67 | 3.54 | 4.77 | |||
| 17-12, 20:00 | SD Eibar – Getafe CF |
49% | 33% | 19% | 1X | 7 | 2.14 | 3.12 | 3.31 | ||
| 17-12, 20:00 | UD Levante – Albacete Balompie |
65% | 17% | 18% | 1 | 1.58 | 3.65 | 5.52 | |||
| 17-12, 20:30 | Sporting Lokeren – KAA Gent |
42% | 28% | 30% | 12 | 2.39 | 3.17 | 2.74 | |||
| 17-12, 20:30 | Yellow Red KV Mechelen – Club Brugge |
24% | 17% | 60% | 2 | 4 | 3.96 | 3.59 | 1.76 | ||
| 17-12, 20:45 | Tottenham Hotspur – Newcastle United |
51% | 26% | 23% | 1X | 10 | 1.70 | 3.53 | 4.40 |
