| 22-01, 20:30 |  Tottenham Hotspur – Norwich City |
62% | 13% | 25% | 1 | 5 | 1.39 | 4.91 | 7.28 | ||
| 22-01, 20:45 | Club Brugge – SV Zulte Waregem |
49% | 25% | 26% | 12 | 6 | 1.22 | 5.47 | 10.22 | ||
| 22-01, 20:45 | Nottingham Forest – Reading FC |
31% | 35% | 34% | 2.00 | 3.29 | 3.61 | ||||
| 22-01, 20:45 | Vitória Guimarães – FC Porto |
14% | 17% | 68% | 2 | 4.23 | 3.48 | 1.73 | |||
| 22-01, 20:45 | Ross County FC – Heart of Midlothian |
21% | 19% | 27% | 2.96 | 3.18 | 2.29 | ||||
| 22-01, 20:45 | Kilmarnock FC – Celtic Glasgow |
26% | 25% | 49% | 12 | 5 | 10.49 | 5.00 | 1.26 | ||
| 22-01, 20:45 | Glasgow Rangers – FC St Mirren |
56% | 19% | 26% | 1 | 6 | 1.10 | 7.78 | 20.01 | ||
| 22-01, 20:45 | AS Bari – Sicula Leonzio |
48% | 26% | 26% | 1X | 5 | 1.22 | 4.72 | 9.96 | ||
| 22-01, 20:45 | Reggio Calabria – Virtus Francavilla |
48% | 29% | 23% | 1X | 5 | 1.23 | 4.66 | 9.57 | ||
| 22-01, 20:45 | Sambenedettese – Fano Calcio |
37% | 18% | 45% | 12 | 1.60 | 3.32 | 4.88 | |||
| 22-01, 21:00 | Stade de Reims – Paris Saint-Germain |
23% | 29% | 49% | X2 | 6 | 9.46 | 5.24 | 1.26 | ||
| 22-01, 21:00 | CF Badalona – Granada CF |
45% | 17% | 37% | 12 | 4.96 | 3.61 | 1.61 | |||
| 22-01, 21:00 | Tenerife CD – Real Valladolid |
29% | 33% | 39% | 2.77 | 3.12 | 2.39 | ||||
| 22-01, 21:00 | Girona FC – Villarreal CF |
21% | 36% | 43% | X2 | 2.90 | 3.16 | 2.28 | |||
| 22-01, 21:15 | Manchester United – Burnley FC |
64% | 21% | 15% | 1 | 8 | 1.43 | 4.41 | 7.50 |
