| 23-11, 16:00 |  West Bromwich Albion – Sheffield Wednesday |
56% | 19% | 26% | 1 | 4 | 1.99 | 3.34 | 3.58 | ||
| 23-11, 16:00 | Real Betis – Valencia CF |
32% | 41% | 27% | 1X | 2.35 | 3.42 | 2.92 | |||
| 23-11, 16:10 | Al Ahli Doha SC – Sadd SC |
69% | 15% | 15% | 1 | 1.63 | 3.78 | 3.97 | |||
| 23-11, 16:30 | Ludogorez Rasgrad – Lokomotiv 1926 Plovdiv |
51% | 24% | 26% | 12 | 5 | 1.40 | 3.93 | 6.59 | ||
| 23-11, 18:00 | AC Milan – SSC Napoli |
27% | 39% | 35% | X2 | 3.09 | 3.37 | 2.22 | |||
| 23-11, 18:30 | RB Leipzig – 1. FC Köln |
79% | 12% | 9% | 1 | 1.39 | 5.12 | 6.97 | |||
| 23-11, 18:30 | Manchester City – Chelsea FC |
78% | 12% | 9% | 1 | 1.41 | 5.12 | 6.52 | |||
| 23-11, 18:30 | Granada CF – Atletico Madrid |
13% | 27% | 59% | 2 | 6 | 4.83 | 3.04 | 1.91 | ||
| 23-11, 20:00 | FC Metz – Stade de Reims |
22% | 47% | 31% | X2 | 4 | 2.82 | 2.79 | 2.72 | ||
| 23-11, 20:00 | Stade Brestois 29 – FC Nantes |
33% | 42% | 25% | 1X | 2.84 | 3.05 | 2.50 | |||
| 23-11, 20:45 | Turin FC – Inter Milan |
16% | 35% | 49% | X2 | 4 | 3.93 | 3.46 | 1.90 | ||
| 23-11, 21:00 | Real Madrid – Real Sociedad |
68% | 23% | 9% | 1 | 1.36 | 5.26 | 7.29 | |||
| 24-11, 17:30 | Sheffield United – Manchester United |
35% | 20% | 45% | 12 | 3.49 | 3.18 | 2.18 |
